Is there a Vitiligo gene?

There is no one gene associated with Vitiligo, it is a combination of genetic and environmental factors. It was first discovered around 1950 by Tindel that Vitiligo has a genetic component. It is a complex genetic relation though, a combination of 50+ genetic markers impact Vitiligo.

It was shown that the co-occurrence of Vitiligo in identical twins was around 23%. Same study showed that you have a 7% chance of being diagnosed with Vitiligo if you have a first degree relative with it.

I found these research papers really useful to read:

• https://www.spandidos-publications.com/10.3892/etm.2021.9743

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362127/

• https://www.sciencedirect.com/science/article/pii/S0022202X20316870